Search for Genetic Material and DNA as Genetic Material

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Search for Genetic Material and DNA as Genetic Material: Overview

This topic briefs on differents experiments which lead to the discovery of genetic material. It explains in detail Grift, Avery, Macleod and McCarty's and Hershey-Chase experiments.

Important Questions on Search for Genetic Material and DNA as Genetic Material

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Negative regulation of protein synthesis is accomplished by

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The replication of chromosomes by eukaryotes occurs in a relatively short period of time because

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The type of recombination that commonly occurs between a pair of homologous DNA sequences is,

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The piece of equipment, that introduces DNA into cells via DNA-coated microprojectiles is known as

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The series of experiments done by F. Griffith involved which of the following bacterium:

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MacLeod, McCarty and Avery determined that R strain bacteria transforming into S strain bacteria because of:

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Experiments of Griffith on mice explained the phenomenon of:

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Which of the following organic molecule has a main role to play in the inheritance?

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Given below are two statements:

Statement I: RNA mutates at a faster rate.

Statement II: Viruses having RNA genome and shorter life span mutate and evolve faster.

In the light of the above statements, choose the correct answer from the options given below:

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Unequivocal proof that DNA is the genetic material was first proposed by

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Assertion: DNA is transmitted from one generation to the other without any change or alteration.

Reason: DNA is carrier of genetic information.

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In Hershey and Chase experiment radioactivity is detected in supernatant when: 

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A series of experiments were conducted by Frederick Griffith in 1928, on transforming principle with :

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Motivated by the classic experiment of Fredrick Griffith and the work of Avery, MacLeod and McCarty to identify the transforming principle, a scientist redesigned and perfromed the experiment with S-strain and R-strain of Streptococcus pneumonae as summarised in the table below:

Treatment Experimental Conditions
T1 S-strain (heat killed) injected into mice
T2 S-strain (heat killed) + R-strain (live) together injected into mice
T3 Nucleic acid isolated from S-strain (heat killed) + R-strain (live) incubated with RNAse and injected into mice
T4 Nucleic acid isolated from S-strain (heat killed) + R-strain (live) incubated with DNAse and injected into mice
T5 S-strain (live) injected into mice
T6 R-strain (live) injected into mice

From the options given below, identify the outcome of the treatments (T1 to T6) on the viability of the mice.

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Choose the correct option for the conclusion of the Hershey-Chase experiment.

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Oswald Avery, Colin MacLeod and Mc Carty (1933-44) worked to determine the _____ nature of 'transforming principle' in Griffith's experiment?

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Which criteria for substance can be acted as genetic material is not fulfilled by protein

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DNA is a preferred over RNA genetic material due to one of the following reasons:

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Match the column I and column II and choose the correct combination from given option.

Column I (Name of organism) Column II (Length of genetic content)
A. Bacteriophage lambda P. 6.6×109 bp
B. Diploid human cell(Nucleus) Q. 4.6×106 bp
C. Bacteriophage φ×174 R. 48502 base pairs (bp)
D. Escherichia coli S. 5386 nucleotides